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Lemoncat

11/11/20 8:41 PM

#332716 RE: Jhawker #332709

saying the RBL’s aren’t legitimate and qualified organizations



How did you get that from this:

Prurisol worked flawlessly in the lab.

Brilacidin's chances couldn't look any better though.



It was merely a cautionary tale about apparently bullet proof preclinical results. Particulalary those in our own history.

I don’t see any truth in his statement.



Which line of the two lines I wrote were untruthful? The control mice looked like Psoriatic lepers. The Prurisol-treated mice were ready for a Maybelline commercial.

Go IPIX!

loanranger

11/11/20 8:47 PM

#332723 RE: Jhawker #332709

"but I cannot imagine why it would not work in humans since it is going against the same virus it worked on in the lab"

LC couldn't let that statement pass. Who could? It makes an assumption that the pharmaceutical community, both big and "developing", knows to be unreliable.

Prurisol worked GREAT on psoriasis in the lab. Just ask the mice. It even seemed to work in mild to moderate human patients, if not in the moderate to severe population.
But when push came to shove it got the heave-ho.

Whether the RBL’s are legitimate and qualified organizations has no bearing on the issue. No one questioned the pre-clinical Prurisol work.

It's fair to point out the prurisol example until it no longer applies. It still applies and only a successful B-CV P2 trial will make it go away.
Remember that in case you're tempted to say anything as ill conceived as "but I cannot imagine why it would not work in humans since it is going against the same virus it worked on in the lab".