Thanks for the response. This is my first "large" investment. I've worked in the medical field for over 25yrs and the science is powerful. I'm hoping/confident in time there will be approvals. I'm willing to wait as long as it takes. I've only recently become very active in managing my own investments. There are several people I always review their comments trying to gain more insight from different perspectives (you included). This board has good and bad. I can't believe how relentless the shorts are on this board. Good lesson's to learn. I try to tune out the noise and focus on the science. GLTUA