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daemon57

10/28/20 8:52 PM

#126950 RE: Amatuer17 #126944

Apparently they hit PE and SE with 775 patients according to their PR. I guess with some $ and an N high enough one could probably hit both as long as you have the money, time and a choice to which ends to hit.

Plenty of room for therapeutics but good for them.

GLTU/A.
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Borel Fields

10/29/20 11:21 AM

#127037 RE: Amatuer17 #126944

Regeneron: Great news for some patients, very small societal impact.

The clinical outcome - at least one subsequent visit to an MD - was reduced from 6.5% to 2.8% - that is, 37 people out of 1,000 treated won't have that next visit.

Great for them, but, in the big picture, that probably means 1 or 2 fewer deaths per 1,000 treated.

Even projecting use in only their sickest cohort, it's hard to WAG a savings of 5-10 lives per 1,000 treated. How many doses are available?

The "trial of the sickest" (CD-12) will show vastly higher lives saved per (very limited) available dose.