Aarthi Narayanan, Associate Professor, National Center for Biodefense and Infectious Diseases, received $35,000 from Innovation Pharmaceuticals, Inc., for a project in which she is examining the use of Brilacidin for the treatment of coronavirus infections.
Brilacidin is an investigational new drug. It is a polymer-based antibiotic currently in human clinical trials. It represents a new class of antibiotics called host defense protein mimetics, or HDP-mimetics, which are non-peptide synthetic small molecules modeled after host defense peptides.
As part of this project, Narayanan will first determine the EC50 values, or the concentration of the drug that gives a half-maximal response.
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