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farrell90

08/13/20 2:14 PM

#318665 RE: thefamilyman #318657

The Oralogic trial in normal volunteers is probably the best data for Brilacidins lack of systmic absorption to date. It has been studied in several other trials with the same result.


"Serial blood samples were collected through 24 hours post-dose to assess absorption of oral Brilacidin from the colon. Blood level analysis, using a sensitive limit of quantitation in plasma of 1 ng/mL, demonstrated no quantifiable Brilacidin concentrations at any timepoint across treatment cohorts and shows containment of Brilacidin within the target location."

http://www.ipharminc.com/press-release/2020/2/13/innovation-pharmaceuticals-phase-1-trial-of-brilacidin-for-ulcerative-colitis-meets-primary-endpoints-positive-topline-results-of-oral-brilacidin

GLTA Farrell