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roiresearch

09/02/20 9:45 AM

#321941 RE: roiresearch #317885

aug 30th

From this information and knowledge of other viruses like HIV-AIDS, Ebola, Influenza, Hepatitis C, or Malaria (4, 5), we have suites of anti-viral and other compounds that can potentially mitigate the damage of the virus on the body, including Remdesivir, Tocilizumab, Favipiravir, Galidesivir, Brilacidin, and Dexamethasone (5). In particular, Remdesivir, which resembles the structure of an HIV reverse-transcriptase inhibitor, has shown promise for reducing recovery time of patients in acute stages, and the steroid Dexamethasone, used widely to fight serious inflammatory reactions, was shown to reduce Covid-19 deaths. Drugs that block spike, membrane, or envelope proteins on the viral shell of coronaviruses are actively being sought, and some are being investigated in clinical trials.

https://www.biorxiv.org/content/10.1101/2020.08.28.271965v1.full

roiresearch

09/02/20 9:58 AM

#321949 RE: roiresearch #317885

here's an aug pre print for narayanan on a drug being developed by pfe. wonder if where that rumor about a month ago started. could have been part of the same GMU research for brilacidin.

In an effort to identify therapeutic intervention strategies for the treatment of COVID-19, we have investigated a selection of FDA-approved small molecules and biologics that are commonly used to treat other human diseases


https://www.biorxiv.org/content/10.1101/2020.08.12.246389v1.full