Replies to post #301359 on Innovation Pharmaceuticals Inc (IPIX)

[MinnieM]

So sorry to hear about your family member. Burns are tough to deal with. I took in a teenager for about a year while his single mother took care of his brother that had serious burns. It's a harrowing job even when released from the hospital.

You bring up some good points regarding potential usage of Brilacidin for burn victims.







Message in reply to:

Sitting in the ICU burn unit of Shands at University of Florida since 5/23/20, watching over a 17 year old member of our family with 40% third and fourth degree burns covering everything from head to waist has presented multiple moments that SCREAMED for Brilacidin. Burn victims experience a cytokine storm, primarily of iL1 and iL6. Cortisol and inflammation are off the charts. Kidneys shut down and/or become damaged. Then infection sets in. Opportunistic lung, blood, and then the mother of all infections: FUNGAL stemming from the fertile ground of necrotic tissue that can run as deep as bone. This boy is fighting skin and skin structure infection. He’s fighting self-destructive Inflammation. He’s fighting Fungal infection from Candida, Fusarium, Aspergillus, and Mucor and the current standard of treatment is Amphotericin-B, which is highly toxic to the kidneys, even as the kidneys are already failing under the burden of fluid loss and decreased cardiac efficiency. The patient is often on dialysis before Amphotericin-B is administered. Fungal infection by itself in the case of Mucor, imposes a 50-100% patient mortality. For older patients, it is a death sentence. Brilacidin’s MOA hits on every one of these battle fronts. Every single one, according to the data we have. A drug Specifically designed for Skin and Skin Structure Infections, Anti-inflammatory, Anti-Bacterial, Anti-Fungal, Anti-Viral, and surely more tolerable than the current standard of care for fungal infection. The moment this drug breaches the levy, wherever that breach occurs, I expect a cascade of demand for it in every field of medicine.

[GreenBioAnalyst]

Hmmm... that is definitely a systemic burn with 40% TBSA followed by multiple organ failures or MODS are fatal. Your typical scenarios. Hopefully, no serious inhalation injury while the patient is intubated. Infections and sepsis are the other serious things to watch out for as well.

I feel for him and for that teenager and his family going through that ordeal. I'm so sorry to hear that. Let's hope and pray that teenager recovers very soon.

And yes, Bril is not just an antibacterial drug. The anti-inflammatory properties should help too in your burn victims.

[TradingPro]

Warren, really sorry to hear that ! My prayers are with you all! The short attack on this Co has prevented the pipeline from advancing to where it could have saved many lives. I suspect some of the shorters and lawyers that made this attack knows a family member where one of
IPIX’s drug would have helped them whether it’s CV-19 or cancer. Remember Buda’s warnings about Karma, it does come back at you and there will be Hell to pay.

[thefamilyman]

Very well said regarding Brilacidin! And our prayers are with your family member...

[duchamp]

This is a heartbreaking story. I wish everyone well. I am mad at myself for feeling sad that I will have to cash out of IPIX after years of waiting to break even. Both my husband and I are self employed and now out of work. So waiting any longer for this to turn around to help us financially, is probably out of the question. I don't even have a right to complain given the story you shared with the board. Take care

duchamp