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BonelessCat

05/26/20 10:37 AM

#298726 RE: Minnesinger #298708

Yes, good catch. There is a difference. In the monkey cell line B directly inhibited SARS-CoV through disruption of the viral envelope. In today’s kidney cell line, the report stated B prevents cell entry “ by blocking the SARS-CoV-2 Spike 1 (S1).”

However, it goes on to say “We now have preliminary in vitro data from two separate independent laboratories that, cumulatively, support Brilacidin’s ability to act directly on the novel coronavirus, as a virucidal agent, and prevent viral binding to host cells.“

So, the report confirms two actions of B, it is both inhibitory and virucidal.