InvestorsHub Logo

BrilBlvR

05/21/20 12:22 AM

#297953 RE: GreenBioAnalyst #297952

Thanks GreenB..Well said

farrell90

05/21/20 12:55 AM

#297955 RE: GreenBioAnalyst #297952

Thanks, nice post. I agree with most of your comments,but oral Brilacidin has been shown numerous times to not be absorbed systemically. A number of reports have shown a GI form of Covid 19 which could respond to oral therapy. I am not aware of any reports linking the GI disorder with later severe pulmonary failure.IMO Brillacidin for Coronovirus will be limited to IV therapy at this time.

IPIX has hinted at the development of an inhaler for Brilacidin to be used for COVID 19 and a diverse group of pulmonary disorders such as asthma, Copd, cystic fibrosis. Hopefully they can receive funding for the inhaler for Covid19. Approval would open the door to the lucrative lung disease market and would be a significant therapeutic addition to treatment as inhaled steroids and bronchodilators have significant side effects.

CytoDan's Leronlimab is an interesting drug. Its antiviral MOA is to prevent viral cell attachment which may be complimentary to Brilacidin.

Influenza is a RNA virus which seems to have structural similarities to Covid 19. Brilacidin could be a possible treatment for influenza pneumonitis which would be an exciting addition.

I agree we have enough data to warrant clinical trials for Brilacidn for Covid 19. IPIX has stated they are being planned and an announcement could only be weeks away.

I expect the flow of funds into IPIX will increase week to week as the news gets out. It really does have that much potential.

I am glad I am not short.The ride from the $4.90 high could end abruptly...very soon.

GLTA Farrell

livefree_ordie

05/21/20 7:33 AM

#297965 RE: GreenBioAnalyst #297952

Thank you for some sanity. Appreciate it. I am with you here.

LilyGDog

05/21/20 7:59 AM

#297973 RE: GreenBioAnalyst #297952

Great contribution to this board. Thanks!

Go Leo & IPIX!

"Clinical applications for Bril would include but not limited to prophylaxis, therapeutic, and as an adjunct combo to any complementary drug out there. That's practically three applications, but two should be enough since the IV portion could be easily repurposed for moderate, severe, and critically cv19 patients. The oral pill should suffice for many as a preventative and for mild or even moderate patients, to halt the progression to severe and critically ill patients.
Ipix could send shock waves if they decide to use Remdesivir as the placebo. They should. Practically, all nucleotide inhibitors are now useless! Bril is more likely to be effective than Leronlimab, Imo, since upregulation of defensin mimetics is enough to trigger an adaptive immune response to make its "indirect" antiviral effects but also in addressing severe patients with pneumonia and/or sepsis.

Now it will be interesting how TIH will look at this in terms of funding.
Will they run the IV portion only Or will they the po version as well for preventative? I expect grants and or funding to happen soon. A partnership could happen too as well, IMO. BRIL SHOULD ALSO WORK FOR OTHER PANDEMIC FLU, which is another business opportunity for IPIX.

Not worried about the next readout. It's in the bag already, some are just a bit slow or unable to assess or foresee things rather quickly; Pass the salt please!

If you find yourself betting against the company, what are you going to do about it? Checkmate! Both sides will catch fire and it's just a matter of time before this sp hits $1, $2, or higher. The valuation is very cheap here with IPIX and it's long overdue for a major correction!

My assumptions about their science have been spot on. The next readout will confirm that as well. GLTA.

We appreciate your business!


TAGB"