Replies to post #295638 on Innovation Pharmaceuticals Inc (IPIX)

[Morfeyus]

I really don’t think there is a vaccine in the near future, in spite of what Fauci says. I think he is having to walk a fine line with an erratic and temperamental boss, so I’m taking what he says with a grain of salt. Also, looking at the timelines of previous vaccines, none are under a 10 year timeline. A recent one ( HPV ) took 15 years to market. Yes brilliant minds are working on it , but to even have one in 18 months seems to me to be overly optimistic...
JMO

[farrell90]

Thanks for posting the link. It is possible Brilacidin has 2 antiviral mechanisms of action which may minimize the effects of single mutation. The first described mechanism of action was the disruption of the viral coat the second was the neutralization of the main protease, the M protein,which prevents viral replication.

Many viruses require multiple medications for optimal treatment. Viruses such as AIDS, Hepatitis C, and Ebola require multiple antivirals for control and that may be the what is required for Covid19.

Brilacidin's dual mechanisms of action could be complimentary. The disruptions of the cell wall would increase Brilacidin's {or a second anti viral if given} intracellular concentraion to disrupt viral replication. Remdesivir appears to stop viral replication by being incorporated into the viral RNA to stop replication.

Due to their different mechanisms of action the combintion of Brilacidin and Remdesivir may prove to be effective.

Brilacidin could be the only pharmaceutical which can kill Coronavirus inside and outside the cell as well as providing immunity to the host.

The reports I have read suggest coronvirus will mutate as all viruses, but the rate of mutation seems to be relatively slow. Unfortunately it will take years of study to understand the whole picture.

GLTA, Farrell