Replies to post #291378 on Innovation Pharmaceuticals Inc (IPIX)

[livefree_ordie]

Assume the professionals involved know which delivery system to deploy here, as a layperson I am ill prepared to offer advice in this area as it is not my expertise. Just seems that if a drug has a good possibility at affecting the course of a deadly virus currently killing thousands of lives that there would be expediency going on here to get things moving forward. Mixture will be very important and delivery methodology for sure, but experts should be working on something now just seems everyone is sitting on their hands while thousands die. Just my perception here now. TOOOOOO SLOOOWWWW. Get on with it already.

[Zdubble17]

LK just asking your thoughts, you say it may not get to surface area of lungs using it through IV. May I ask how it was given to people through IV and cleared up ABSSSI? As I said this is a talking point and a question thrown out there because I don’t know the answer. Also I wonder if this could be given through a some sort of nebulizer treatment directly into lungs. No clue like I said WAG. Look forward to a response.

[farrell90]

Do you have any documentation for that theory; that IV Brilacidin would be ineffective for treating pulmonary infections?

I am certain any clinical trial for Brilacidin for Covid19 will be by IV.IV Brilacidin worked well for ABSSSI. It had good pharmacodynamics and blood levels and in fact worked as well as Daptomycin.

Sorry but most cases of severe pneumonia are treated with IV medications. They easily penetrate pulmonary tissues.

Your premise is unfounded, unless you can document otherwise.

"Try it how? Injection? Enema? Oral rinse? Those are the current proven delivery methods. It’s possible that an IV , circulatory system, won’t deliver sufficient B to the infection site. For oral rinse and enema, there was no systemic absorption."

GLTA Farrell

[Empiricst1]

Try it how? Injection? Enema? Oral rinse? Those are the current proven delivery methods

LilKahuna, I didn't think there was an injection option for any B use. Wish there were. A few here have said there was, but I never saw it. Hope it is just my bad.

[MinnieM]

One of the doses on ABSSSI was IV, not injection. Typo?





Message in reply to:

Try it how? Injection? Enema? Oral rinse? Those are the current proven delivery methods. It’s possible that an IV , circulatory system, won’t deliver sufficient B to the infection site. For oral rinse and enema, there was no systemic absorption. B worked because it was delivered directly to the inflamed site. So, it’s quite possible that IV delivery would not deliver B from circulation across alveoli to inflamed Interior surface cells.

Let the labs work out the delivery through testing, otherwise should there be right to try, there is a high risk of setbacks (perceived failure) due to inefficient delivery method.