Replies to post #142980 on NanoViricides Inc. (NNVC)

[Nanotoday]

Why would relying on the consistency of their failure be a foolhardy predictor of future success? Seems like a very reliable predictor.

[KMBJN]

Regarding if they can make a successful coronaviricide, yes it's hard to predict. Ebolacide didn't work very well, but Ebola had an unusual shape, so not sure if that played into it or not. Many of their other drugs were successful when tested in cells and animals, including flucide and herpecide. So, based on the consistency of the success in cells and animals, there are decent odds that they can make a coronaviricide that works in cells and animals.

Whether they can get government funds or not, they have a poor record - depending on whether or not Seymour was forthcoming in describing how close they were to previous funds from the feds.

All developmental stage biotechs are failures until they prove their drugs are safe and effective in clinical trials in humans, get FDA approval, sell their drugs at a profit, and make money for investors.

So they are all consistently failures with accumulated losses for many years until they are not.

Most fail.

NNVC has failed to even get an IND and their drugs into humans, which is pretty bad. This is likely to be the next step for them - to test herpecide in humans.

They have been successful testing their drugs in cells and animals, but that is only the first step.

Will see how far they get.

"It's tough to make predictions, especially about the future."

[drkazmd65]

A straightforward and justified viewpoint at this point.

If one was willing to rely on the consistency of the failure of those things over the last X number of years, however foolhardy that might be, they wouldn't find it hard to predict those things at all.

We know - for example - that the amount of a potential flu-cide that they would have needed to be able to produce to do Toxicity testing was far beyond their capabilities prior to the last year or so. I may - in fact - be beyond their capability now.

And as a Coronavirus-cide would almost certainly have to be ingested or injected, rather than a topical treatment like the Shingles-cide - in order to get a reasonable toxicity testing experiment done they would have to be able to produce the candidate drug in a similarly large quantity to Flucide, It is a huge "IF" that they could do even that.

And that is after 'assuming' that the AEC2 mimic ligand actually works and doesn't need to be tweaked or redesigned,...

Whether NNVC makes it or not - that's going to depend on the Shingles treatments. Unless somebody with really deep pockets and an agenda can push it forward - there's not much chance that a coronavirus-cide is going to come out before either this epidemic gets out of control, or burns itself out.