Just to confirm my impression of the HOT data released this morning, I asked Dennis (aka biotech2k on IV) to comment on the data. He posted the following: "The best response is Stable Disease? I see no CR or no PR. That means the official RECIST 1.1 ORR is 0% and the Clinical Benefit Rate is 50%. I don't see anything there that makes me want to rush out and buy. I hope that helps." He has a very good grasp of the science and has been mostly right about many companies. My $0.02.