Replies to post #182748 on Kraig Biocraft Laboratories Inc (KBLB)

[igotthemojo]

"He knows how to make spider silk from goat milk."

guess again..he knows the tech..

"Even if he did know the tech, you really think Randy Lewis would steal the tech"

he doesn't have to steal anything...lol...its a scientific process...and he knows the process"

"and give it to the Chineses?"

you mean show them the process?...im pretty sure he already has...and they no doubt paid him a ton of money..

just remember...if kim can mass produce, he hopes to be able to make 8 tons this year...

the Chinese have the capacity for 150,000 tons because that's how much silk they produce every year...and have been for a very very long time..

on shark tank, mr wonderful says if larger companies can do what you are doing and can do it 10 times faster and 10 times bigger, then you are a cockroach...lol

china can likely do it 1000 times bigger and far faster than kblb…

"BT, Amsilk, and others try to pirate KBLB ship."

utter nonsense...they are into synthetic spider silk and always have been..

"The current share price is worth .14. Put the company up for sale and it will fetch billions."

so you think kblb can be bought for 17 times the current pps?..don't you think if kblb was worth $2 bil, the pps might just be a bit higer?..or at least going up instead of dropping like a rock?...

smh

[WebSlinger]

This was from about 6 months ago. Imagine what they have accomplished in the past 6 months (unlike KBLB who has done practically nothing).

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July 12, 2019

Spider silk is an engineer’s dream material. Lightweight, strong, elastic and biocompatible, it’s an ideal building block for a myriad of applications, including medical implants, body armor and vehicle components. But trying to farm spiders, which eat each other and yield relatively small quantities of silk, is impractical.

Utah State University researchers, under the direction of USU USTAR Professor Randy Lewis, have pioneered initial, lab-scale production of synthetic spider silk through the use of transgenic goats, bacteria, alfalfa and silkworms. Now, the researchers are using emerging CRISPR technology to harness the spinning power and efficiency of silkworms. Their results demonstrate promise for use of transgenic silkworms as natural spider silk spinners for industrial production of high-performance fibers.

Lewis and team members Xiaoli Zhang, Linjin Xia, Breton Day, Thomas Harris, Paula Oliveira and Justin Jones, along with colleagues at Pennsylvania’s Drexel University and China’s Soochow University, published their findings in the May 6, 2019, issue of the American Chemical Society’s Biomacromolecules journal.

“Developing a way to spin synthetic spider silk fibers in a consistent, high quality, cost-efficient and environmentally friendly way for commercial-scale production has been a challenge,” says Zhang, lead author on the paper and postdoctoral fellow in USU’s Department of Biology.

The project is the team’s first attempt with CRISPR/Cas9 – short for “Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein-9 nuclease” – a variation of a naturally occurring immune system found in bacteria. Like a pair of molecular scissors, CRISPR/Cas9 enables gene editing.

“Prior to using CRISPR, our attempts to insert spider protein DNA into transgenic hosts were somewhat random,” Lewis says. “CRISPR offers much more precision.”

And that precision is paying off. The researchers are reaping the spinning benefits of silkworms, organisms used for centuries by humans for silk fiber production. But they’re also discovering the offspring of CRISPR/Cas9-assisted transgenic silkworms, and subsequent generations of offspring, are retaining the spider silk protein genes.

“This is a breakthrough,” Lewis says. “Before CRISPR, offspring from transgenic worms eventually lost the spider silk genes.”

To test the effectiveness of transgenic spider silk protein inheritance, Zhang inserted green and red fluorescence gene tags before and after the spider silk genes in the transgenic silkworms’ DNA sequence. Her investigation also revealed spider silk generated by the offspring of transgenic silkworms is getting stronger.

“We found the incorporation of spider silk protein isn’t disrupting the structure of silkworm protein,” Zhang says. “In fact, the spider silk protein is adding to the crystallinity and thus, mechanical properties of the transgenic silkworms’ silk, particularly strength.”

https://www.usu.edu/today/story/usu-researchers-use-crispr-to-advance-synthetic-spider-silk-manufacture