Your rational optimism has always calmed me and at this point, I’m too stubborn to get out. I agree with you and I originally got in for HIV only. We seem to be chasing too many rainbows but the science remains strong, folks on the drug continue to thrive and no adverse effects. (I still scratch my head that with all of that, the FDA hasn’t green lighted combo).
My frustration now is Naders promise on a partner. Anything short of having a deal next week is bad. I will continue to hold (and complain LOL) until I see something substantive on the business end.