Novel drug-regulated transcriptional networks in brain reveal ... https://bmcgenomics.biomedcentral.com › articles by M Korostynski - ?2013 - ?Cited by 24 - ?Related articles Sep 8, 2013 - Therapeutic classes of drugs are coded by colors presented on the clustering .... that is connected to pharmacological properties of the drugs. ..... fold of change compared to saline control, foldmean - mean fold change from ..... Levy SE: Microarray analysis in drug discovery: an uplifting view of depression.
Assessing Concordance of Drug-Induced Transcriptional ... https://journals.plos.org › ploscompbiol › article › journal.pcbi.1004847 by JJ Sutherland - ?2016 - ?Cited by 24 - ?Related articles Mar 30, 2016 - Author Summary Gene expression studies in model systems are ... may still successfully infer properties of a drug (classification) via those of ... In this work, the ensemble of 9071 fold change values is denoted as gene-level analysis. ..... We defined components of variation (dose, time, overall transcriptional ...