Sorry, no comprendo. In plain english, what do you mean ? :-)
Dropouts could be higher and still a success ?
I do fully agree, like I said previously, dropouts could be up to 30% and still a success, but that 's not my point
My point is that if Cel SCI requires, for significance purpose, less than 15.5%, then we have a winner, I will bet my bottom dollar, 100% garantied.
If dropouts are only contained by the fact that they need 298, we can't conclude with such certainty, dropouts, necessarily high because of low survival expectation, could go from a wide spectrum from 20% till 60% and trial continue with no significance at risk