Daviddal, It would be great to get some human data on an Aricept/Ampakine combo treatment. With the synergism seen preclinically, a lower dose of the Ampakine could presumably still work well. It seems like most patients are on the Aricept/Namenda combo now, so a 3 drug combo study would also be interesting. If we had data like that now, partnering CX-717 for AD might be easy, even with the dosing limitations.