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Replies to post #150856 on Arrayit Corporation (ARYC)
Multi-Allergen Testing—At initial diagnosis, when a patient’s allergies are unknown, it may be necessary to test for multiple suspected foods, especially since a third of allergic children react to more than one food [31]. Furthermore, testing against purified allergen component proteins in addition to conventional whole food extracts is emerging as a useful clinical tool, for example in predicting severe allergy and anaphylaxis [35, 36]. Low Blood Volume Testing—While the need is growing to test patients for multiple allergens, this need is particularly problematic in infants/children where it is often difficult to collect sufficient blood volume to perform these multiple tests. For example, venipuncture from small children is difficult to accomplish and normally requires a highly skilled phlebotomist. Risks include bleeding and/or bruising, injury from restraining of the child, discomfort and mental stress for both the child and parents [37]. Low blood volume collection such as through a finger- or heel-stick is especially important for pediatric patients.
ThermoFisher ImmunoCAP ISAC is an immunoassay platform that allows for simultaneous measurement of specific IgE antibodies to 112 different allergen components using only 30 µl of serum or plasma. Capillary blood sampling can be used, thus enabling a less invasive procedure for testing young children.
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