Cat, in spite of what many say here (i.e. the science doesn't work, the science is outdated, the science is worthless), there is clear evidence that it DOES work. Is it better as part of a combo treatment? I think that's clear, too. I believe MANY existing treatments will be more effective when combined with other agents. The progress has been much slower than anyone likes or anticipated and the missteps by management are legend but I still believe, if management gets its act together, we could have a treatment that will be successful and (maybe) we could make our money back.
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