Misiu - I love your confidence about never needing a Phase 3. I am so excited now more than ever and it's hard not to check for pending PR's every day!
While confidence in product is a good sign - this is mid leading over confidence
They are starting dose escalation study in an important and difficult area. Even co has put 18 and then 30 patient as sequence to show PFS which takes years.
You telling that FDA drug approval based on 18 patients enrolled in dose escalation shows high unrealistic expectations.