Reviewed your various w/s, other calculations provided by M\B posters and have spoken with the surgical oncologist who treated a now deceased family member (died from the cancer).
Her opinion, looking at your projections and her experiences, is that the trial might conclude within the next six to eight weeks (good efficacy) and then proceed to the next step. If her opinion is correct, the shorts are already toast and large money has missed the dinner bell.
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