Phase 1 trials are really just for testing safety, which isn't necessary for Bryostatin considering how it's been tested earlier in much higher doses for decades.
They might need a P1 for the synthetic version though. That's probably also what they'll use to develop the oral version of the drug.
Traumatic Brian Injury is one that’s also been mentioned. Believe they have tested in mouse models and I have some memory of the military testing it in the field.
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