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thesaud

12/15/18 9:56 AM

#19291 RE: FDApproved #19289

One of the questions asked by sell side analysts was, at what percentage of improvement would you say is significant, and Dr. Landis replied 20 % or more. we should beat that without even trying to hard. The thing I worry about is that patients in the trial have other serious health problems that could kill them b4 finishing the trial. these are very sick people.
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Auto1

12/15/18 10:18 AM

#19294 RE: FDApproved #19289

Why not 3 placentas? So... a placenta is not a placenta. Some placenta's are more equal than others? Seems this potentially adds several magnitudes of complexity to 'placenta selection' for maximum efficacy...

Will placentas from different donors need to be kept separately? Are they sorted and segmented based on HLA?

How do we know that the 'selective nature' of efficacy based on 'sickest receive greatest benefit' is a function of the miracle of the placenta VS. pluristem spin on HLA matching, antibodies yet undescribed, etc. etc.

Lots of questions...

Will the studies performed from single placenta now be required to use 'different' placentas, mixed, to evaluate for greater efficacy/safety in other indications??