Replies to post #7 on Delivra Corp (fka DLRVF)

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Delivra publishes positive results using its platform technology for topical Advil™ (ibuprofen) and Celebrex™ (celecoxib)

http://www.stockhouse.com/news/press-releases/2018/12/17/cgx-energy-announces-definitive-rig-agreement-for-use-of-the-ralph-coffman-rig

CNW Group
December 11, 2018, 8:00 AM AST
TORONTO , Dec. 11, 2018 /CNW/ - Delivra Corp. (TSXV: DVA - "Delivra" or the "Company") today announced the publication of positive data from a pre-clinical study demonstrating the safety and efficacy to treat pain directly with a topical version of Advil™ (ibuprofen) and Celebrex™ (celecoxib). Testing for effects on joint pain and inflammation; topical Delivra-ibuprofen and Delivra-celecoxib formulations offer sustained long-term pain and swelling reduction, compared to oral equivalents. These results were published in the respected peer-reviewed scientific journal, Journal of Pain Research, under the title, "Penetration and efficacy of transdermal NSAIDs in a model of acute joint inflammation". The article may be found at the following link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239099/?report=reader

In pre-clinical testing, undertaken by an independent third-party research organization, the Delivra-ibuprofen and Delivra-celecoxib formulations provided sustained pain reduction. In the study, both Delivra formulations were tested in an acute dog model of arthritis where the formulation performed equally or better for swelling and pain reduction compared its oral equivalent and test controls. This exemplifies Delivra's technology, with its multi-laminar system, is capable of gradually releasing the active ingredient to the area of need. This transdermal, designed "slow release" is a valuable and highly advantageous characteristic of the topical Delivra-ibuprofen and Delivra-celecoxib creams and may offer significant advantages over oral medication. These formulations will provide better localization of the drug at the site of need, yielding quicker and longer lasting relief.

"This impressive data further validates Delivra's platform technology by outperforming oral delivery and offering patients an effective, safe and convenient cream for pain management. Our robust pharmaceutical pipeline of high-value innovative products, including Delivra-ibuprofen and Delivra-celecoxib formulations, provide an array of unique commercialization opportunities. As such, we will continue to pursue out-licensing opportunities for major global markets to unlock the value of our portfolio," said Dr. Joseph Gabriele , CEO of Delivra.

For these two formulations, the Company has two PCT patent pending applications.