Replies to post #222330 on Biotech Values

[dewophile]

i am a statistics idiot so sorry in advance if this is a dumb question but why would the confidence interval for the HR be over 1 w p<.05

[DewDiligence]

AZN’s Imfinzi and Tremelimumab fail in second-line H&N cancer:

https://www.astrazeneca.com/media-centre/press-releases/2018/update-on-the-phase-iii-eagle-trial-of-imfinzi-and-tremelimumab-in-advanced-head-and-neck-cancer-07122018.html

[Neither] Imfinzi monotherapy [nor] the combination of Imfinzi plus tremelimumab…[met]…the primary endpoints of improving OS compared to SoC chemotherapy…