Goldenisla - In HIV Pro140 is not allowing virus to enter the cell and replicate .
In cancer Pro 140 , by blocking CCR5 is blocking cellular invasion .
“ CCR5 is a crucial receptor in the growth , invasion and metastasis of human cancer “
Many patients with breast cancer over express or re-express CCR5.
In the cancers patients we see CTC ,
(Circulating tumors cells ) , they promotes metastasis .
Possibly Pro 140 decreases CTC by blocking the CCR5 receptor .
But
“During the study a number of correlative studies will be measured to better understand the mode of action of Pro 140 , CTC. “
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