Replies to post #1910 on Conatus Pharmaceuticals Inc. (CNAT)

[lorema]

No, it has to be a reduction on at least 20% from baseline.

[Inoviorulez]

No. it would have to be higher from control. stat sig. although placebo doesn't do anything in respect to HVPG.

In essence in the pilot study

8 out of 12 patients achieved a > 10% reduction

and 4 out of 12 patients achieved a >20% reduction.

So the company chose to only recruit patients with over 12 mmHg (mercury) meaning severe portal hypertension.