AGN would probably argue that with experienced injectors this wouldn't be the case. The fact AGN is looking to develop a longer acting product using the same amount of toxin though argues that they themselves don't believe that simply doubling the dose is the solution RVNC can counter detail this assertion by using published data showing that higher doses of botox don't result in longer duration (it is in their slide decks). They also have their own data showing even with experienced injectors higher doses do in fact lead to higher rates of ptosis