Sage Therapeutics has a market cap of 7 Billion recently more than doubling from the $70s. They are working on depression drugs with none approved. GABA and you guessed it NMDA drugs. Ketamine of which AV-101 mimics but with more safety is approved as an Anesthetic and you guessed it again as Opioid substitute or adjunct to opioids for pain. If AV-101 is a safer and nearly as effective thus more widely used than Ketamine then as the Jackie Gleason character in the “Honeymooners” would say “..........” Alice! Go VTGN. “...........” Alice!