SAFETY **AND** futility are therefore now non issues.
overall survival is NOT the **SOLE** criteria.
H&N patients sometimes lose their sense of taste for the remainder of their lives. some have to take a $200 a month lubricant to counter radiation/chemo.ETC
QUALITY OF LIFE issues ,IMO are also to be considered.
OPDIVO cost 300% more than MK and cures ZERO patients. Then there is is $17K booster shot every few months ( takes 30 minutes ).
The list of OPDIVO BAD side effects is LONG & SERIOUS.
***MK??? constipation/diarrhea.***
It cost a fortune to trash CVM. AVERAGE position size is,31+ K shares.