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DewDiligence

08/14/18 1:34 PM

#220495 RE: jondoeuk #220494

Gritstone—...This has been shown to induce greater numbers of antigen specific T-cells and increases the quality of response by involving multiple subsets and cytokine profiles

Increases compared to what, specifically? TIA

DewDiligence

08/23/18 10:46 AM

#220588 RE: jondoeuk #220494

BLUE, Gritstone ink cancer-drug-development collaboration:

https://finance.yahoo.com/news/bluebird-bio-gritstone-oncology-announce-103000354.html

Under the terms of the agreement, Gritstone Oncology will provide 10 tumor-specific targets across several tumor types and, in certain cases, TCRs directed to those targets to bluebird bio. Gritstone Oncology will receive $20 million in an upfront payment and an additional $10 million in the form of a Series C preferred equity investment. In addition, Gritstone Oncology is eligible for significant development, regulatory and commercial milestones on any therapies, and tiered royalties on certain approved therapies.

…bluebird bio will conduct all development, manufacturing and commercial activities. Gritstone Oncology will utilize its proprietary technology platform to enable patient selection for clinical development of such therapies.