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PlentyParanoid

08/02/18 2:02 PM

#236010 RE: DaubersUP #236005

Daubers. No it is not. It is based on p2a headcount and responses. I feel very uncomfortable with any guess estimate for PASI 75 response corresponding to increased dose (one assumption more). I did, however, provide in my answer to SS confidence intervals based on PASI 75 responses in p2a with p2b head counts plus p-value sensitivity analysis accounting also for trial size. They do look better.