Replies to post #44929 on OncoSec Medical Inc (ONCSQ)

[dangerM]

It's the same study/authors as in post 44902? So obviously you already have hschlauch's educated opinion provided on this. :-)

https://www.nature.com/articles/s41591-018-0085-8

A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments
Kevin C. Barry, et. al.

"Intratumoral stimulatory dendritic cells (SDCs) play an important role in stimulating cytotoxic T cells and driving immune responses against cancer. ..."

https://www.ucsf.edu/news/2018/06/410911/immune-profile-successful-cancer-immunotherapy-discovered?utm_source=ucsf_tw&utm_medium=tw&utm_campaign=2018_cancer_immunotherapy_prediction&utm_term=

"... In the new study, which was led by postdoctoral researcher Kevin Barry, PhD, Krummel’s team first demonstrated – using publicly available melanoma genomics data from The Cancer Genome Atlas (TCGA) and tissue samples from clinical collaborators at UCSF – that the number of SDCs in human melanoma tumors predicted improved response to immunotherapy and overall survival, as they had seen in mice. ..."