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Zeev Hed

09/09/03 4:48 PM

#25854 RE: RIVERCITY DAN #25853

I take it they are waiting for the Raptiva FDA decision. Frankly, the stock run in anticipation, and with psoriasis, that is a tough call. Placebo effect is usually around 25%, many psoriasis drugs failed at the FDA because they could not be shown to have an impact substantially better than placebo. There are some issues of safety with Raptiva, and the rumor inciting the run yesterday) was that these are no longer a concern, My fear is more whether they pass the test of "effective", where comparison with placebo comes into play. When it reopens? I know not. If the results are good, it may gap up big, but, if bad, it could be halved, that is a pure case of Russian roulette...