Replies to post #22628 on Cytodyn Inc (CYDY)

[BlueHorseshoe13]

56.1% low dose.

[misiu143]

I agree with all of you , about 53 %!with low dose , it should be much , much better with higher dose .

In my opinion 53% without serious side effects for HIV is very good ,

And no rebound in viral load and no resistance after such a long time .

Patients who didn’t respond never were offer higher dose , we don’t know how many could do well with it

[trding]

We knew that number would be around that 53-56%, ~21/40. I don’t believe that is a surprise, see my link below. The safety data looked great imo.

Participants who experienced virologic rebound moved to Follow-up Phase and restarted oral combination ART. Once ART was reinitiated, all 18 virologic rebound patients achieved viral suppression to less than 50 HIV-1 RNA copies/mL, with mean time to viral suppression of 46.6 days.

Participants experiencing virologic rebound were followed for up to 24 to 36 months after re-initiation of baseline ART and showed no long-term virologic or clinical consequences as a result of rebounding on PRO 140 monotherapy

In summary, this trial showed that PRO 140 was potent enough and well enough tolerated that a substantial fraction of people could be suppressed on it alone for over three years. Over that time, there were no non-injection site AEs, no anti-PRO 140 antibodies detected, no selection of X4 virus, and even those who failed could universally be re-suppressed by returning to their original regimens

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=136676840