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InTheTrenches

05/20/18 2:17 PM

#6277 RE: InTheTrenches #6276

I just looked up the inclusion criteria for the last Phase 2 trial:

https://clinicaltrials.gov/ct2/show/NCT02431468?term=bryostatin&rank=2

The inclusion criteria does require imaging to confirm probable Alzheimer's:

"Neuroimaging (computerized tomography (CT) or Magnetic Resonance Imaging (MRI)) within the last 24 months consistent with a diagnosis of probable Alzheimer's disease (AD)"

runncoach

05/20/18 2:35 PM

#6278 RE: InTheTrenches #6276

My educated guess would be that the percentage of misdiagnosed would be lowered greatly by the advanced stage of the disease. Supposedly the mean number of years since first diagnosis in our trial was roughly 5 years. Also one of the reasons a placebo group of similar diagnosis length is vital I suppose.