Replies to post #22183 on Cannabix Technologies Inc (BLOZF)

[Money $hot]

IMO U have conjured up a wild Crystal Ball Theory:

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Though . . . the Big Folks Companies would probably rather shy away?

AMG - Shy away from what? I'm assuming you believe the whole point of this (Cannabix) investment is heavily weighted to Law Enforcement by way of legalization of Marijuana? Therefore, Big Tech/Pharma would rather take a pass versus sully their reputations? I believe the "tech" is much bigger than Marijuana and/or Controlled Substances. You are failing to recognize the other side of the coin (equation). Which is the Early Disease Detection side of the patented mission. Cannabix and Breathtec are two sides of the same coin (device). The attraction to the technology crosses many sectors worth unfathomable billions and actually trillions, but whose got time to do all that counting - right?

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Tech advances are so rapid in current world economy, that BLOZF reasonably only has say until July 2019 to have testing and product out for sale?

AMG - There are "tech" advances that can take decades to get to the next level. So how does 2019 suddenly become the doomsday year? I think you have no clue about the advancement of FAIMS technology or the folks @ Cannabix/Breathtec behind this leading science. Please allow me to try and paint a much bigger picture.

WHAT is High-Field Asymmetric Waveform Ion Mobility Spectrometry?

FAIMS is a new technology capable of separation of gas-phase ions at atmospheric pressure (760 torr) and at room temperature. FAIMS can be operated over a wide range of pressures and has been tested above 1500 torr. FAIMS will operate at lower and higher temperatures.

FAIMS is the worlds first atmospheric pressure ion focusing device

Ion focusing means that the ion density increases, analogous to the light intensity increase due to a focusing lens. In other words, the ions are brought into closer and closer proximity to each other as time passes. The ion cloud is compressed, or focused, in volume. Two forces try to expand the ion cloud, ion-ion repulsion and diffusion. In FAIMS these two forces are overcome and the ions are forced together. The ion cloud increases in density (the number of ions per unit volume). No other means of compressing the ion cloud (at atmospheric pressure) exists. In a vacuum, devices such as quadrupoles and ion traps can do this, but these devices fail at higher pressure. FAIMS is the worlds first atmospheric pressure ion trap

Ion trapping is fairly simple. An ion trap mass spectrometer can isolate and hold ions without loss. Unfortunately those devices fail at higher pressure . Only FAIMS can collect and hold ions in a confined place (thus trapping them) at atmospheric pressure .

www.faims.com/what.htm

Ion-mobility spectrometry–mass spectrometry

Ion-mobility spectrometry–mass spectrometry (IMS-MS), also known as ion-mobility separation–mass spectrometry, is an analytical chemistry method that separates gas phase ions on a millisecond timescale using ion-mobility spectrometry and uses mass spectrometry on a microsecond timescale to identify components in a sample.

History

Earl W. McDaniel has been called the father of ion mobility mass spectrometry.[1] In the early 1960s, he coupled a low-field ion mobility drift cell to a sector mass spectrometer.[2]

In 1996 Guevremont et al. presented a poster at the ASMS conference [8] about IMS-TOF. In 1997 Tanner patented a quadrupole with axial fields which can be used as a drift cell for IMS separation. He also mentions the combination of these quadrupoles with an orthogonal TOFMS.[9]

This work led to the development of an ion mobility-quadrupole-CID-TOFMS instrument by Micromass in the UK and ultimately led Micromass / Waters corporation to develop of the worlds first commercial ion mobility-mass spectrometer instrument in 2006.

In 2013, Agilent Technologies released the first commercial drift tube ion mobility-mass spectrometer named 6560 with an 80 cm drift tube. Ion funnels are used to improve the ion transmission efficiency. The design thus greatly improved the sensitivity of ion mobility and allowed commercialization.[12][13]

Instrumentation

High-field asymmetric-waveform ion-mobility spectrometry (FAIMS or RF-DC ion-mobility spectrometry) is a mass spectrometry technique in which ions at atmospheric pressure are separated by the application of a high-voltage asymmetric waveform at radio frequency (RF) combined with a static (DC) waveform applied between two electrodes.[15][16] Depending on the ratio of the high-field and low-field mobility of the ion, it will migrate toward one or the other electrode. Only ions with specific mobility will pass through the device. It is well known that the high RF field distort the conformation of the ions, FAIMS thus is a separation technique without reserving the structure of the ions and the CCSs of the ions cannot be measured.[17] Because FAIMS is a mass selector (other ions are excluded), the sensitivity in the scan mode is much lower than that of the drift tube ion mobility (all the ions are analyzed). Therefore, FAIMS is usually coupled with triple quadrupole mass spectrometer which is also ion selection type instrument.

en.wikipedia.org/wiki/Ion-mobility_spectrometry–mass_spectrometry

Triple quadrupole mass spectrometer

A triple quadrupole mass spectrometer (TQMS), is a tandem mass spectrometer consisting of two quadrupole mass analyzers in series, with a (non-mass-resolving) radio frequency (RF)–only quadrupole between them to act as a cell for collision-induced dissociation. This configuration is often abbreviated QqQ, here Q1q2Q3.

History

The arrangement of three quadrupoles was first developed by J.D. Morrison of LaTrobe University, Australia for the purpose of studying the photodissociation of gas-phase ions.[1] After coming into contact with Prof. Christie G. Enke and his then graduate student Richard Yost, Morrison's linear arrangement of the three quadrupoles probed the construction of the first triple-quadrupole mass spectrometer.[1] In the years following, the first commercial triple-quadrupole mass spectrometer was developed at Michigan State University by Enke and Yost in the late 1970s.[2] It was later found that the triple-quadrupole mass spectrometer could be utilized to study organic ions and molecules, thus expanding its capabilities as a tandem MS/MS technique.[1]

Applications

The triple quadrupole mass spectrometer allows for increased sensitivity and specificity yielding lower detection and quantitation limits.[8] For these reasons, employment of the TQMS is a vital asset in the fields of drug metabolism, pharmacokinetics, environmental studies, and biological analyses. In most drug and pharmacokinetic studies, animals like rats, are subjected to a new drug in order to probe how the substance metabolizes in the body. By analyzing the rat’s urine or plasma with a triple quadrupole coupled to liquid chromatography, the concentration and fragmentation pattern of the new drug can be determined.[8] In environmental and biological studies, the triple quadrupole is useful for quantitative studies that involved identifying whether or not specific substances are present in a sample.[9] One of the more common uses of a triple quadrupole mass analyzer is for structural elucidation, which provides information about fragmentation patterns. [10] However, a mass spectrum only provides information about fragmentation, which isn’t enough information to fully deduce the structure of a molecule or compound. So for the purpose of structural elucidation, it is paired with data obtained from other analytical methods, like nuclear magnetic resonance (NMR) spectroscopy and infrared spectroscopy (IR), for a more accurate analysis.

en.wikipedia.org/wiki/Triple_quadrupole_mass_spectrometer

To make a Long(s) story short...Since 1960 there have been advancements in our tech space. The difference maker for Cannabix/Breathtec (Daughter & Mother) is Professor Richard Yost has been @ the forefront of our technology since 1970 (48 years). Professor Yost is The Godfather of FAIMS Technology. Agilent Technologies (a multi-billon dollar player) recognizes Yost's ongoing contribution to the science (pushing the envelope), which is why Agilent Technologies is riding his coattails every step of the way.

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USA Administration will do something wild like impose tariffs tickets on
testing Positive for MJ, if randomly tested on USA Side?

Huh? The war (prohibition) on marijuana is effectively over (see California Proposition 64). As more and more folks seek MJ recreation/medication...a Controlled Substances breathalyzer will cause no more havoc than a BAC breathalyzer.

To reiterate, our tech comes from decades of experience played at the highest level. Were simply here to witness history and ride them coattails.

Monopoly Man



Just 1 opinion coupled to some important facts,

/////AMG

P.S. I would be remiss not to mention the overall valuation of Breathtec (Mother Company). It is unfathomable that Breathtec would be valued @ 5 Million USD (minus cash on hand) on any given day. The tech itself is the golden key. It's Borderline Boardroom Criminal Management @ Breathtec.

[x1power]

Nice post!
I could not even begin to top it, as I am not student of science.
That said, let us not forget that politics will rule tech.

Where is the evidence (surely not in present stock price and volume),
of anyone in big finance reaching to grasp this Mobile MS tech?

Odds are very much not in favor of Vanc. B.C. registered stock company of
being anything but a one-shot wonder?

I will take a chance that we just might get a July 2018 Federal Recreational MJ Law passed, Stock Pop Effect.

I wish the best to our thoughts this tiny company might just be an
Apple undiscovered.

Perhaps this year . . . we shall observe U of Florida move the ball . . . and the Game is On. I must assume they possess in School, a business department, without looking it up.