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locicat1

05/10/18 4:41 PM

#5637 RE: LW89 #5629

Some needed corrections for accuracy purposes. First, the LDN Crohn's clinical study to which I referred was performed by another research group in the Netherlands and not at what I believe you really meant-Pennsylvania State University NOT University of Pennsylvania that you indicated(UPenn). The study was both a clinical endpoint study and a mechanistic study designed to (1) attempt to define the mechanism of the observed clinical effect(s) (2) examine any other effects that has bearing on the observed positive clinical outcome.