Replies to post #11503 on Pluristem Therapeutics Inc (PSTI)

[EichKing]

I can’t help but think of Kevin Bacon getting flattened in the Animal House scene repeating “ all is well”...”all is well”....same as PSTI PPS getting flattened.

[zzaatt]

Replacing the clowns is only a pipe dream
With all the milestone gibberish the original clown spewed
Just too bad the spineless clown couldn't just admit their failures

All this in one post!!!!!
This obscene abuse heaped on the executives that are
about to bring to fruition the next major advance in medicine?
An endless stream of invective, interspersed with a barely
comprehensible word salad, where maybe every third or fourth
sentence is minimally comprehensible? Yep! PATHETIC!!!

the now laughable, "the process is the product".

First, congratulations for laughing without
using up any part of your anatomy, that's progress!

Unfortunately, once again, Scotty repeats the nonsense he and
the other nasties have been "spewing" about the value of Pluristem
having it's own production facilities.

Allo generously and helpfully provided us with a link to an excellent
article. As I said in a previous post, if you're a serious investor here, you owe it
to yourself to read it, couple of times!

What I've said before, one of the most revolutionary aspects of
MSC therapeutics is that what the patient gets is a living piece
of a human organ, capable of responding dynamically to the needs
created by the target pathology. This is not an inanimate small molecule
medicine where the manufacture can be easily outsourced to any competent lab.
Full control of the creation of the cells, from induction to final quality
control and verification is essential.

The following are excerpts from the article:

Cell Characterization: Quality, Identity, and Biological Activity

Routine testing performed on all PLX cells manufactured includes measurements of cell quality and safety, identity, and potency. Cell quality and safety measurements include viability, postthaw recovery, karyotype, sterility, endotoxin, and mycoplasma. Cell identity tests include % fetal cells and immunophenotyping analyses. Functional tests are defined by the downstream clinical application and, in the case of fetal PLX cells, include the ability to induce BM (Bone Marrow) migration in vitro and the secretion of various cytokines

Managing this process depends on deep knowledge and hands-on experience.
Every vial of living cells had to be cajoled into differentiating functionally
to be responsive to the pathology at hand, and to be reliably uniform from
from batch to batch!!

Still laughing Scotty??

Read this article, you'll be impressed and finally understand the
importance of Pluristem's internal production capabilities!.
Yes indeed, "the process is the product".