It will pass but you can have only so many stumbles before you break something. Death in late stage trials where all of the patients are dying and results are measured in months of survival are to be expected. But they have reach the end of the line for scruwing the pooch, raises, retention bonuses, shares, no significant deals for long period, long silence, burn through cash without taking any action until they are almost out of cash, offering at $2, now fda hold. Time to make significant news or sell, they simply may not be able to succeed with the resources they have, investment banker time soon.