It is funny how the belief that big pharma is aware of everything medicinal on the planet is so wide spread. I used to work there and I have news to you:
Relative to typical education and training levels in big pharma the density of 'lazy bastards' and 'sheer idiots' may be higher there than in general population> The density of narrowly focused minds and over inflated egos certainly is. A lot good to great science slips by because of that.