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Investintin

02/28/18 12:54 PM

#284882 RE: Jimmy Joe #284880


Okay, then I'll try to explain myself:

This technology is a pro-drug, it has a molecule attached to the opioid that prevents the opioid to have any effects.

In order to release the opioid, the pro-drug needs an enzyme that is only found in the GI... this enzyme will release the opioid for it to have an effect.

The technology can be adapted to extended and immediate release.

Because it needs to be processed in the GI for the opioid to have an effect, then it cannot be abused via nasally, smoking or IV.

Additionally, the pill has an inhibitor that is activated with very high doses of the opioid, therefore preventing an overdose and preventing dead.

If a patient needs a higher dose, either can have one or two or three more pills (as long as it is within the safe limits)

If the concentration reaches a dangerous dose, then the inhibitor prevents and overdose.

and because this is a tablet (not a capsule with beads), the tablet can be cut into small pieces for smaller doses (as you mentioned before).

even if you cut it, it cannot be abused because it needs to be metabolized in the GI.


Unless you can find a healthcare professional that will prescribe different strengths at the same time (the scatter gun script), an insurer who will pay for that type of script, your solution for the O D medication is very limited
with regard to those who are in a pain management program and whose pain is not at a constant level.




So, no one needs to prescribe different strengths, and the dose can be adjusted, at the same time as preventing and overdose.


No matter how you try to slice and dice this wonderful cutting edge technology you just cannot get away from the fact that it is very limited.



Yes, it is limited to drugs that can be abused, or that have a life-threatening overdose risk... therefore not suitable for vaccines or antibiotics