Replies to post #212003 on Innovation Pharmaceuticals Inc (IPIX)

[CallMeCrazy]

Sounds like the oncologic precision medicine trend is our (kevetrin) friend.

From Sox post #212005---
As for Kevetrin, the current K-OC trial's secondary endpoint is tumor response so we'll have some idea of its efficacy at three times per week. If the efficacy data are impressive, IPIX can take advantage of FDA’s new initiative to approve a drug based on a biomarker. For K it could be p53/p21.

FDA approves first cancer treatment for any solid tumor with a specific genetic feature

“The U.S. Food and Drug Administration today granted accelerated approval to a treatment for patients whose cancers have a specific genetic feature (biomarker). This is the first time the agency has approved a cancer treatment based on a common biomarker rather than the location in the body where the tumor originated.

IMO, Kevetrin will be a major player in many targeted cancer therapies.

Message in reply to:

Indeed - more on Dream of Precision Med in Oncology

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https://www.cancer.gov/about-cancer/treatment/types/precision-medicine

The hope of precision medicine is that treatments will one day be tailored to the genetic changes in each person’s cancer. Scientists see a future when genetic tests will help decide which treatments a patient's tumor is most likely to respond to, sparing the patient from receiving treaments that are not likely to help. Research studies are going on now to test whether treating patients with treatments that target the cancer-causing genetic changes in their tumors, no matter where the cancer develops in the body, will help them. Many of these treatments are drugs known as targeted therapies. Our section on Targeted Therapy has more information about these drugs.

Currently, if you need treatment for cancer, you may receive a combination of treatments, including surgery, chemotherapy, radiation therapy, and immunotherapy. Which treatments you receive usually will depend on the type of cancer, its size, and whether it has spread. With precision medicine, information about genetic changes in your tumor can help decide which treatment will work best for you.

There are drugs that have been proven effective against cancers with specific genetic changes and are approved by the FDA. Many of these drugs are discussed in Targeted Cancer Therapies. Approved treatments should be available wherever you have cancer treatment.

[CallMeCrazy]

And even more on the "Dawning of precision medicine".

"Together with comprehensive, precisely structured biobanking, this study represents a major step towards precision medicine," says Professor Mitch Levesque of the Department of Dermatology at the UniversityHospital Zurich. Before they can be used clinically, the insights gained must now be applied in independent studies with higher patient numbers. The method using biobanking, high-dimensional cytometry, and computer-aided pattern recognition should also be useful in clinical decision support and developing new therapeutic approaches when it comes to other clinical pictures.

https://www.sciencedaily.com/releases/2018/01/180108163216.htm