Replies to post #211739 on Innovation Pharmaceuticals Inc (IPIX)

[untohim]

all that and again says nothing imho relating to this trial....your analyses of censorship is not what IPIX is saying at all!! Period.

this is what we know:
Our updated Corporate Overview, with a visual display of the Kaplan-Meier curves....
oral rinse showed a clear separation from placebo in delaying the onset of SOM—particularly the period from approximately 28-42 days, after the initiation of treatment, during which the incidence of SOM rose strikingly in the placebo group while not in the group being treated with Brilacidin

[untohim]

Definition of kaplan meier proportion:

Time-to-event is a clinical course duration variable for each subject having a beginning and an end anywhere along the time line of the complete study. For example, it may begin when the subject is enrolled into a study or when treatment begins, and ends when the end-point (event of interest) is reached or the subject is censored from the study (more on this later). This duration is known as serial time, describing the clinical-course time, in contrast to calendar (also known as secular) time.


In preparing Kaplan-Meier survival analysis, each subject is characterized by three variables: 1) their serial time, 2) their status at the end of their serial time (event occurrence or censored), and 3) the study group they are in.

The following terms are commonly used in survival analyses.

Event: Death, disease occurrence, disease recurrence, recovery, or other experience of interest

Proper administrative censoring does not have any affect on Kaplan Meier estimate, because it is executed after the last event/failure, and censor has an effect to Kaplan Meier proportion only if it has an event/failure follwing it.