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frrol

12/21/17 9:23 AM

#209342 RE: DaubersUP #209340

Consistently doing something like that. Great. I'll grudgingly admit that, not that I denied it in the first place. Your point?

Yes, we'll see. Great hope that there was a dose dependent trend there in the lower dose cohorts that extends into these doses. Fingers crossed!
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F1ash

12/21/17 9:34 AM

#209348 RE: DaubersUP #209340

It’s certainly worth considering that since patients taking the 400mg dose only represent a very small percentage of the “blinded average response rate”, that group could have stellar efficacy and it would be nearly imperceptible in the still blinded results.

Even double or triple the previous response rate from only ~14% of patients in the trial would not make the overall numbers look that good until unblinding imho.

Besides isn’t it “buy the rumor” ? :-)