IMO MRNS ganax probably won't work in PPD. MRNS ganax efficacy is pretty weak vs SAGE-547 or SAGE-217. This analysis by Ohad Hammer is pretty old but probably still applies.
which started in Nov 2016 and ending in Jan 2019. At the last update Oct 2017 they managed to enroll 10.
MRNS was a good short term trade. In July I got in @1.53, sold it quickly 2 months later for @3.06. At this price, I am not sure if it is a good short term trade.