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slcimmuno

12/03/17 10:16 AM

#205763 RE: biodoc #205760

Agree — Pru PsO... 24/10 PASI 75 active to placebo and we should be good to go ... Ph 3 ... this is exactly what CELG saw in an early Ph2.

Below best overview on Biologics I’ve come across. Nitty gritty. Detail.

“Treatment goals for psoriasis: Should PASI 90 become the standard of care?”
http://www.actasdermo.org/en/treatment-goals-for-psoriasis-should/articulo/S1578219015000505/

Otezla showing a close to $2bn market for a moderately effective, safer, fewer side effects, oral non-biologic... PASI 75 the bar, not PASI 90/100, as to Efficacy...

Re B OM — yeah, def looking fwd to the data/results