Replies to post #215287 on Biotech Values

[biomaven0]

>>Are RIP1 and RIPK1 one and the same?

Yes.

Necroptosis is an alternative cell death pathway different from the more familiar caspase-dependent apoptosis. It involves three kinases - RIPK1, MLKL and RIPK3 of which RIPK1 appears easiest to target. GSK has a RIPK1 compound in trials in IBD, so it has potential applications outside the CNS.

Peter