Where did you pull 1 in 5000 from. Wait, don't tell me. You are so blatantly wrong - you would make Trump blush!
Below are the 10 year success rates (published 2014)
Phase 1 to 2: 64% Phase 2 to 3: 31% Phase 3 to NDA: 58% NDA to PDUFA approval: 85% Phase 1 to approval: Just shy of 10%
1 in 5000 is .02%. You are off by a factor of 500. Most companies have multiple drugs in their pipeline so the chance of getting 1 of their drugs to market increases with each additional drug.